Headed by Dr Eric Rubinstein, DR Inserm

Goals: To understand the function role of tetraspanins microdomain, their physiological role and their involvement in diseases, in cell differentiation, cancer progression, cellular fusion and stem cell trafficking


1.Regulation of Notch signaling by TspanC8 tetraspanin  
2.Deciphering the mechanisms of muscle cell fusion via the study of tetraspanins and physiopathological implications
3.Targeting Tspan8 in colon cancer and melanoma